Abstract
A system is described which is capable of measuring small changes in corneoscleral dimensions of eyes under varying conditions of intraocular pressure stress in vivo. The system consists of an optical interferometer, a fringe counting system, and an automatic recording system for digital data storage. The light source for the interferometer is a helium-neon laser. Corner cube reflectors serve as mirrors in both arms of the interferometer making optical alignment virtually automatic and eliminating problems associated with small-angle ocular rotations. One corner cube is mounted on an acrylic corneal contact lens, the combined weight being less than 100 mg. This assembly is glued to the cornea of an experimental animal and serves as the spatial reference for the anterior surface of the eye. The skull of the anesthetized animal, rigidly fixed in a special holding apparatus, serves as the posterior reference. The fringe counting system is capable of tracking the position of the apex cornea to ±0·316 μm at velocities up to 600 μm/sec. Relative position of the corneal apex is recorded and stored in digital format for later computer analysis. The technique of using the shift in the position of the corneal apex to estimate changes in intraocular volume during pressure stress is discussed.
Published Version
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