The state of autonomic regulation in patients with postcastration syndrome after transplantation of human fetal tissues

Abstract

The functional state of the autonomic nervous system was evaluated in 38 women after total ovariectomy. Clinical analysis of autonomic disorders and challenging tests indicated the disturbance of autonomic regulation and inhibition of vascular reactivity against the background of total autonomic lability. One month after transplantation of fetal human tissues vascular responses were improved: the number of positive dialatatory reactions increased and moderate pulse waves were recorded. The general condition of the patients improved, their work capacity increased, and sleep patterns normalized, which led to a reduction of anxiety. However, the transplantations had varying effects on hot flashes, which may be associated with their diverse nature. The positive effect that transplantation of fetal human tissues elicited in most patients may be attributed to normalization of their hormonal status.