Abstract
Intravenous transplantation of human fetal tissue, notably of the liver and thymus, is used in emergency hematological states: aplastic anemia and acute leukemia. The strong manifestation of “graft-versus-host” disease proved unexpected. Fetal donor hepatic cells stimulate hemopoiesis in the recipient. In some cases true cellular chimerism has been observed, specifically when a transplant of human fetal tissue (THFT) to a fetus with prenatal pathology was performedin utero. In gene therapy attempts have been made to infuse hemopoietic stem cells intravenously or to introduce the adenosine aminase gene into leukocytes of patients with a deficiency of this enzyme. Treatment using transplantation of human fetal tissue will help solve the problem of HLA-histocompatibility and will make gene therapy more widely applicable.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
