Abstract
The aim of this work was the study of the special features of intraoperative and early postoperative period course in patients with gastroesophageal reflux disease after antireflux surgery carried out from laparoscopic and traditional laparotomy approach. Materials and methods. There were analyzed the results of examination and surgical treatment of 136 patients with gastroesophageal reflux disease treated at SI A.A. Shalimov “National Institute of surgery and transplantology” NAMSU from 2005 to 2015 year. The main group included 93 patients who underwent laparoscopic surgery, the control one – 43 patients who underwent surgery by traditional open method. There was carried out monitoring of the main parameters of vital functions every three hours after surgery, recovery terms of intestine peristaltic activity, pain syndrome intensity, analyzed the dynamics of changes of the typical GERD complaints, its intensity, the development of early postoperative complications. The results of research. Duration of laparoscopic surgeries did not differ from the open ones but intraoperative hemorrhage and prolonged artificial pulmonary ventilation, postoperative patient day were less than in the control group. At the same time the main parameters of the organism vital functions (systolic and diastolic arterial pressure, respiration rate, heart rate, oxygen blood saturation) were better in patients of the main group. In the group of patients operated by laparascopic approach intensity and duration of pain syndrome were less than in patients operated by open approach and also was noticed an early activation and recovery of intestinal peristalsis in these patients. Conclusions. Both laparoscopic and open approaches at antireflux surgeries in early postoperative period are effective. The received data testifies to the less traumatism, less duration of recovery period at videoendoscopic surgeries that by-turn decreases the risk of postoperative complications development, reduces the necessity of medicaments prescription. Laparoscopic surgeries are the method of choice at the surgical treatment of patients with GERD
Highlights
Досліджено поширеність поліморфізму Asp299Gly гену TLR-4 у хворих на ко-інфекцію ВІЛ/ХГС вірусу імунодефіциту людини (ВІЛ)/хронічного гепатиту С (ХГС)
To define the frequency of Asp299Gly polymorphism of TLR-4 gene there were examined 47 patients co-infected with HIV\HCV and 30 healthy donors by the method of polymorphism of the long restrictive fragments (PLRF) – polymerase chain reaction (PCR)
The correlative analysis indicates the reverse dependency between Asp299Gly polymorphism of TLR4 gene and Zn content (r=–0,34; p
Summary
Досліджено поширеність поліморфізму Asp299Gly гену TLR-4 у хворих на ко-інфекцію ВІЛ/ХГС вірусу імунодефіциту людини (ВІЛ)/хронічного гепатиту С (ХГС). ПОШИРЕНІСТЬ ПОЛІМОРФІЗМУ ГЕНУ TLR-4 У ХВОРИХ НА КО-ІНФЕКЦІЮ ВІЛ/ХГС Встановлено, що у хворих на ко-інфекцію ВІЛ/ХГС достовірно частіше ніж в контрольній групі виявляється поліморфізм Asp299Gly гену TLR-4 (χ2=4,5; р
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.