Abstract
BackgroundThe collection of samples from HIV-infected patients is the beginning of the chain of translational research. To carry out quality research that could eventually end in a personalized treatment for HIV, it is essential to guarantee the availability, quality and traceability of samples, under a strict system of quality management.MethodsThe Spanish HIV BioBank was created with the objectives of processing, storing and providing distinct samples from HIV/AIDS patients, categorized according to strictly defined characteristics, free of charge to research projects. Strict compliance to ethical norms is always guaranteed.ResultsAt the moment, the HIV BioBank possesses nearly 50,000 vials containing different prospective longitudinal study sample types. More than 1,700 of these samples are now used in 19 national and international research projects.ConclusionThe HIV BioBank represents a novel approach to HIV research that might be of general interest not only for basic and clinical research teams working on HIV, but also for those groups trying to establish large networks focused on research on specific clinical problems. It also represents a model to stimulate cooperative research among large numbers of research groups working as a network on specific clinical problems. The main objective of this article is to show the structure and function of the HIV BioBank that allow it to very efficiently release samples to different research project not only in Spain but also in other countries.
Highlights
The collection of samples from HIV-infected patients is the beginning of the chain of translational research
Some basically consider any inventory or file of biological material as a Biobank, whereas in other countries Biobanks are seen as the major research infrastructure
To carry out quality research that could eventually end in a personalized treatment for HIV, it is fundamental to guarantee the availability, quality and traceability under a strict system of quality management of samples obtained through standardized techniques that can be used in studies on AIDS
Summary
The collection of samples from HIV-infected patients is the beginning of the chain of translational research.
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