Abstract

To derive and validate a new ecological measure of the social determinants of health (SDoH), calculable at the zip code or county level. The most recent releases of secondary, publicly available data were collected from national U.S. health agencies as well as state and city public health departments. The Social Vulnerability Metric (SVM) was constructed from U.S. zip-code level measures (2018) from survey data using multidimensional Item Response Theory and validated using outcomes including all-cause mortality (2016), COVID-19 vaccination (2021), and emergency department visits for asthma (2018). The SVM was also compared with the existing Centers for Disease Control and Prevention's Social Vulnerability Index (SVI) to determine convergent validity and differential predictive validity. The data were collected directly from published files available to the public online from national U.S. health agencies as well as state and city public health departments. The correlation between SVM scores and national age-adjusted county all-cause mortality was r=0.68. This correlation demonstrated the SVM's robust validity and outperformed the SVI with an almost four-fold increase in explained variance (46% vs. 12%). The SVM was also highly correlated (r ≥ 0.60) to zip-code level health outcomes for the state of California and city of Chicago. The SVM offers a measurement tool improving upon the performance of existing SDoH composite measures and has broad applicability to public health that may help in directing future policies and interventions. The SVM provides a single measure of SDoH that better quantifies associations with health outcomes.

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