The situation of antibiotic resistance of commonly isolated bacterial pathogens at the General Hospital in the Northern mountainous region of Quang Nam

Abstract

Objective: To study the antibiotic resistance situation of some common pathogenic bacteria at the Northern mountainous area General Hospital of Quang Nam in 2020 - 2021. Subjects and research methods: Cross-sectional study, retrospective data on medical records of patients who used antibiotics, had positive bacterial culture tests. Results: 475 pathogenic bacteria strains were isolated, of which Gram-negative bacteria accounted for 65.3%, Gram-positive bacteria accounted for 34.7%. The 5 bacterial species isolated with the highest proportion were Escherichia coli (27.4%), Staphylococcus aureus (24.8%), Klebsiella pneumoniae (7.6%), Pseudomonas aeruginosa (6.9%), Acinetobacter baumannii (4.8%). Isolated bacteria are highly resistant to many common antibiotics. Staphylococus aureus is highly resistant to Benzylpenicillin (98.3%); Oxacillin (76.1%); Imipenem (76.1%); Erythromycin (76.9%); Escherichia coli is highly resistant to Ampicillin, Ticarcillin (92.3%); Aztreonam (93.8%); Klebsiella pneumoniae is completely resistant to Ampicillin, Ticarcillin (100%); Psedomonas aeruginosa is resistant in 100% to Ampicillin, Amoxicillin/clavulanic, Cefazolin, Cefoxitin; Acinetobacter baumannii is completely resistant to Ampicillin, Amoxiciline/clavulanic, Cefazolin (100%), but they are sensitive to Tobramycin, Amikacin, Ertapenem and Colistin (100.0%). Conclusion: Frequent pathogens are resistant to many common antibiotics. Key words: northern Quang Nam hospital, antibiotic resistance, pathogenic bacteria, E.coli, S.aureus