Abstract
The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to turn the exponentially growing amount of data into knowledge. Here, we provide an overview of SIB's resources and competence areas, with a strong focus on curated databases and SIB's most popular and widely used resources. In particular, SIB's Bioinformatics resource portal ExPASy features over 150 resources, including UniProtKB/Swiss-Prot, ENZYME, PROSITE, neXtProt, STRING, UniCarbKB, SugarBindDB, SwissRegulon, EPD, arrayMap, Bgee, SWISS-MODEL Repository, OMA, OrthoDB and other databases, which are briefly described in this article.
Highlights
Like physics and astronomy, many life science disciplines are continuously producing more and more data
SIB’s Bioinformatics resource portal ExPASy features over 150 resources, including UniProtKB/Swiss-Prot, ENZYME, PROSITE, neXtProt, STRING, UniCarbKB, SugarBindDB, SwissRegulon, EPD, arrayMap, Bgee, SWISS-MODEL Repository, OMA, OrthoDB and other databases, which are briefly described in this article
The 2016 training programme, for instance, is composed of short and long face-to-face courses covering topics such as large-scale data analysis, statistics, algorithms and methods for bioinformatics, network analysis, basic computational tools and the use of high performance computing (HPC) in biological research. It includes courses on specific SIB resources, some of which have been described above. These courses are organized by domains, covering for example the protein resources, the genomic resources and structural biology
Summary
Many life science disciplines are continuously producing more and more data. Isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. UniProtKB/Swiss-Prot (www.uniprot.org) provides comprehensive expert-curated functional annotation for over 540 000 protein sequences, including descriptions of protein function, location, interactions and domain structure, as well as post-translational modifications (PTMs) and variants and their functional impact [18].
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