Abstract

Next to the sea star T and B lymphocytes, we find the IPA (Invertebrate Primitive Antibody). Rosetting test and PFC test after Injection of SRBC (Sheep red blood cells)were performed in the sea starAsterias rubens (Echinodermata). Positive results were obtained and summarized in this work. They indicated the presence of anti-SRBC antibodies in the sea star, according to the method of Cunningham.

Highlights

  • Michel LeclercAbstract—Next to the sea star T and B lymphocytes, we find the IPA (Invertebrate Primitive Antibody)

  • Rosetting test and PFC test (Plaque-forming cell) were clearly shown in the past

  • Cunningham [1] demonstrated the existence of Vertebrate antibodies by the use of the PFC method in 1965. 50 years later we recall a work which was obtained in sea star Asterias rubens after immunizations to SRBC (Sheep red blood cells) in vivo

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Summary

Michel Leclerc

Abstract—Next to the sea star T and B lymphocytes, we find the IPA (Invertebrate Primitive Antibody). Rosetting test and PFC test after Injection of SRBC (Sheep red blood cells)were performed in the sea starAsterias rubens (Echinodermata). Positive results were obtained and summarized in this work. They indicated the presence of anti-SRBC antibodies in the sea star, according to the method of Cunningham. There are no Rosetting with PRBC (Pigeon red blood cells). 2) PFC appear in treated animals but not in controls ( Figure 1- B-C ) It is noticeable that these PFC need no Guinea pig complement to be shown

INTRODUCTION
MATERIALS AND METHODS
CONCLUSION AND DISCUSSION

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