The screening of vascular risk factors for cognitive dysfunction in population with high risk of stroke

Abstract

Objective To screen vascular risk factors for cognitive dysfunction in population with high risk of stroke by cognitive function evaluation on community people with high risk of stroke. Methods A total of 541 subjects who were screened with high risk of stroke from August to December 2012 in Yanta District of Xi'an, Shaanxi were evaluated by collecting baseline data and analyzing vascular risk factors. Mini-Mental State Examination (MMSE) was used to assess their cognitive function. Univariate and stepwise multivariate Logistic regression analysis were used to screen vascular risk factors for cognitive dysfunction in people with high risk of stroke. Results In those subjects, 90 people were identified as cognitive dysfunction, with a prevalence of 16.64% . Univariate and stepwise multivariate Logistic regression analysis showed that diabetes mellitus ( OR = 1.871, 95% CI: 1.132-3.151; P = 0.015) was an independent risk factor for cognitive dysfunction in people with high risk of stroke. Conclusions Vascular risk factors could increase the risk of cognitive dysfunction, especially diabetes mellitus is the independent risk factor for cognitive dysfunction in people with high risk of stroke. DOI: 10.3969/j.issn.1672-6731.2017.02.010