Abstract
Introduction: Depletion of hematopoietic progenitor cells and their mature descendants by the use of anti-cancer therapies often leads to acute myelosuppression. In this condition, hematopoietic stem cells (HSCs) can repopulate the peripheral hematopoietic system. Nevertheless, if this ability of HSCs is compromised, then a fatal and irreversible damage to the hematopoietic system can occur. This can be due to the use of anti-cancer therapies that are particularly toxic to HSCs. To avoid complete depletion of HSCs, there is a need to understand the pathways and mechanisms involved in their survival and regeneration.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
