Abstract

Summary Due to an alarming growth in prevalence, diabetes mellitus (DM) has attained the status of a global epidemic. Most deaths linked to DM are attributable to cardiovascular disease, and the elevation in cardiovascular risk in DM is thought to be underpinned by resistance to the vascular and metabolic effects of insulin. One of the characteristics of insulin-resistant states is the excessive production of reactive oxygen species. Recent studies have highlighted this to be a crucial contributor to the relationship between insulin resistance and cardiovascular disease, leading to research investigating the potential therapeutic implications of manipulating reactive oxygen species levels in the context of insulin resistance. This review summarizes our current understanding and future direction in this emerging field.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.