Molecular Mechanisms Involved in Inflammation and Insulin Resistance in Chronic Diseases and Possible Interventions

Renata Gorjão,Sandro Massao Hirabara,Ji An Pan,Hilton Kenji Takahashi

doi:10.1155/2012/841983

Abstract

Molecular Mechanisms Involved in Inflammation and Insulin Resistance in Chronic Diseases and Possible Interventions

Highlights

Recent studies showed a close relationship between these two conditions, the precise mechanisms are not completely understood. This special issue aimed to join original research and review articles related to the involvement of inflammation and/or insulin resistance with the development of chronic diseases as well as the interaction between these two factors and possible interventions based on important molecular targets
The potential topics for this special issue included (a) molecular basis of inflammation and insulin resistance; (b) crosstalk between inflammatory pathways and insulin signaling; (c) cell and animal models to test and understand the role of inflammation and insulin resistance as well as the interaction of these two factors on the development of chronic diseases; (d) interaction of inflammation and/or insulin resistance in human pathology conditions; (e) factors leading to inflammation and/or insulin resistance in models of chronic diseases; (f) identification of new biomarkers of chronic inflammation and insulin resistance in different models; (g) identification of new molecular targets for reducing inflammation and insulin resistance in chronic disease models; (h) new interventions for preventing or reducing insulin resistance and inflammation based on molecular targets in signaling pathways
Sunflower oil supplementation was able to improve dislipidemia in mice fed with high-fat diet (HFD), it increased inflammatory condition and insulin resistance state induced by the diet

Summary

Introduction

Editorial Molecular Mechanisms Involved in Inflammation and Insulin Resistance in Chronic Diseases and Possible Interventions This special issue aimed to join original research and review articles related to the involvement of inflammation and/or insulin resistance with the development of chronic diseases as well as the interaction between these two factors and possible interventions based on important molecular targets.

Results

Conclusion