Abstract
Background: Atrophy gastritis and intestinal metaplasia are early phenotypic markers in gastric carcinogenesis. White light endoscopy does not allow direct biopsy of intestinal metaplasia due to a lack of contrast of the mucosa. Narrow-band imaging system with magnifying endoscopy (NBI-ME) in the gastric mucosa suggested that the appearance of a light blue crest (LBC) on the epithelial surface may be a distinctive endoscopic finding associated with the presence of intestinal metaplasia. Objective: The aim of the present study was to clarify the value of NBI-ME for diagnosing gastric intestinal metaplasia. Methods: The research was designed as a cross-sectional descriptive study, studied on 52 patients with chronic gastritis in Hospital of Hue University of Medicine and Pharmacy. Results: Gastric intestinal metaplasia was found in 26.9% patients with WLE. LBCs specific for IM were found in 51.9% patients with NBI-ME. The sensitivity, specificity and accuracy of narrow-band imaging were 88%, 81.5%, and 84.6%, respectively. Conclusion: In narrow-band imaging with magnifying endoscopy (NBI-ME), observation of a light blue crest on the epithelial surface in the gastric mucosa is a highly accurate sign of the presence of histological intestinal metaplasia. Key words: gastric intestinal metaplasia, NBI-ME
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