Abstract
Colorectal cancer is a global health problem, which is an economic and humanistic burden for both patients and the state. A growing body of evidence suggests that dysbiosis of intestinal bacteria can contribute to the emergence and development of colorectal cancer by the formation of harmful metabolites and changes in the physiological processes of the host. The aim of the review is to summarize studies on the properties of the intestinal microbiome and mechanisms associated with colorectal carcinogenesis, including inflammation, bacterial pathogenicity factors, biofilm formation, bacterial metabolites and genotoxins, as well as oxidative stress.
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