Abstract
The current study aims to shows the relationship between gene polymorphisms (SNP( of miRNA 146-a of patients infected with otitis media. This finding included 50 samples collected from healthy subject and 100 samples from a patienst suffering from otitis media who attended Al-Sadr Medical City (ENT Department) in Al-Najaf Governorate during the period from February 2022 to June 2022. The samples had an average age ranging from 5 to 70 years. Genotyping of miRNA 146-a revealed the presence of three genotypes: GG, CG, and CC, representing (16%, 47%, and 37%) respectively in patients with otitis media, while it was (27%, 18%, and 55%) respectively in healthy subjects. CG was common in patients while GG was more common in healthy subjects. MiRNA as potential biomarker of patients infected with otitis media.
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