Abstract
This study was conducted to investigate the ameliorative effect of lactic acid bacteria Lactobacillus casei and Lactobacillus acidophilus against Potassium bromate (25, 50) mg / kg toxicity by some physiological indicators in 35 of female rats after 21 days. The animals were divided into 7 groups within each group 5 animals weighted 140 – 155 g. The results showed a significant decrease (P<0.05) in value of Red blood cells (RBC), hemoglobin (Hb), White blood cells (WBC), Lymphocyte (LYM) and Platelets (PLT), While increasing the values of Granules (GRN). Also found that the addition of Potassium bromate Potassium bromate led to increase in cholesterol, triglyceride (TG), Low Density Lipoprotein (LDL) and blood glucose, while decreased the values of High Density Lipoprotein (HDL) for rats groups with increasing the concentration of Potassium bromate compared with control group. The addition of two types of lactic acid bacteria L. casei and L. acidophilus with Potassium bromate showed a positive effect to reducing the negative effect of Potassium bromate on blood and lipid profile parameters compared with the control group and Potassium bromate group. It is concluded that the lactic acid bacteria has protective effects and reduces the effects that Potassium bromate.
Highlights
Potassium bromate (KBrO3) is a white crystal, granules or powder, it has no medicinal value but is added to treat flour for bread and bakery product (12)
Potassium bromate is widely used as improving additive for bread making (4)
The decomposition of bromate ions in bread at low temperatures may be due to the presence of metal ions in flour, which acts as a catalyze(3). (30) analyzed fifteen different bread brands produced in Zaria metropolis of Northern Nigeria to determine potassium bromate content using the iodometric titration method
Summary
Potassium bromate (KBrO3) is a white crystal, granules or powder, it has no medicinal value but is added to treat flour for bread and bakery product (12). Some lactic (35) mentioned that presence of significant acid bacteria (LAB) have been reported to increase of Total cholesterol, triglycerides have cholesterol-lowering effects in animals value and decrease in HDL at the addition of and humans (23).
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have