The role of ct-perfusion for diagnostic of solid renal tumors

Abstract

Introduction. Nowdays, CT and/or MRI do not have sufficient specificity for the differential diagnosis of benign renal masses (oncocytoma and angiomyolipoma with minimal fat) from malignant tumors, and therefore all patients undergo surgical treatment.Purpose and objectives. The aim of the study was to evaluate the diagnostic effectiveness of perfusion computed tomography (PCT) for the differential diagnosis of solid renal masses.Materials and methods. The data of 60 patients (61,28±8,46 years) with primary founded solid renal tumors, who underwent PCT at the preoperative stage, were analyzed. Four perfusion indicators, such as BV, BF, PS and MTT, for the renal masses and normal cortex were evaluated.Results. According to the results of the statistical analysis, the perfusion parameters BV, BF, PS of the renal cortex were significantly higher than in tumors of any histological type (p<0,05). A statistically significant difference was found between clear cell, chromophobe and papillary types of renal cell carcinoma in terms of BV and BF (p<0,05), between benign and malignant tumors — in MTT.Conclusions. PCT has great potential in the assessment of neoangiogenesis and differential diagnosis of solid renal masses.