Abstract
The role of cortisol and thyroid stimulating hormone in prognosis of acute anticholinesterase pesticides poisoned patients admitted to Tanta Poison Control Center
Highlights
Anticholinesterase poisoning is a major global health problem with thousands of deaths each year
The aim of the present study was to evaluate the prognostic role of cortisol and thyroid stimulating hormone (TSH) in acute anticholinesterase pesticides poisoned patients admitted to Tanta Poison Control Center
Patients: This study was a prospective cohort study conducted on patients suffering from acute anticholinesterase pesticides poisoning who were admitted to the Poison Control Center of Tanta University Emergency Hospital, Tanta, Egypt, between August 2019 to end of July 2020
Summary
Anticholinesterase poisoning is a major global health problem with thousands of deaths each year. Previous studies reported that cortisol and thyroid stimulating hormone (TSH) may have prognostic role in patients poisoned by organophosphates. Aim of the work: Evaluation of prognostic role of cortisol and TSH in acute anticholinesterase pesticides poisoned patients admitted to Tanta Poison Control Center. Results: TSH has no prognostic role, but cortisol has predictive role in mortality, need for ICU admission and intubation. Anticholinesterase pesticides are common to be used in Egypt due to their wide availability and cheap prices. They are considered to be frequent reasons for admission in hospitals and intensive care units (ICU) in developing countries (Arafa et al, 2017 & Elagamy and Gaber, 2019). TSH in turn drives the thyroid gland to synthesize and secrete thyroid hormones (Abo Elfottoh et al, 2020).
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