The role of chronic prostatitis in the pathogenesis and progression of benign prostatic hyperplasia

Abstract

Objectives To investigate the role of chronic prostatic inflammation in the pathogenesis and progression of benign prostatic hyperplasia (BPH). Methods We enrolled 356 patients with BPH from May 2011 to December 2014 in our hospital were analyzed retrospectively. According to the pathological results, all patients were divided into the BPH with prostatitis group and BPH group. Age , prostate volume (PV), PSA, IPSS, and acute urinary retention (AUR) of the two groups were analyzed. Results In the BPH with prostatitis group, 121/356(34.0%) patients were be confirmed as BPH with prostatitis, the other 48/121(39.7%) patients were be confirmed as acute urinary retention (AUR). In the BPH group, 235/356(66.0%) patients were be comfirmed as simple BPH. and there were 60 (25.5%) patients with AUR. There was no significant difference in patient's age between the two groups (P>0.05), but PV , PSA, IPSS and incidence of AUR in the BPH with prostatitis group were higher than BPH group (P<0.05). Conclusions The patients with BPH and prostatitis have some characteristics of bigger volume, higher PV, PSA, IPSS and incidence of AUR. Chronic prostatic inflammation may be has important role in the pathogenesis and progression of BPH. Key words: Prostatic Hyperplasia; Prostatitis