The role of cerebroplacental ratio in predicting fetal growth restriction

Abstract

Objective To explore the role of cerebroplactic ratio (CPR) in predicting fetal growth restriction (FGR). Methods The clinical data of 52 pregnant women with FGR and 49 normal pregnant women, who were admitted to the Second Affiliated Hospital of Guangzhou Medical University from January 2015 to December 2017, were retrospectively analyzed. ROC curve was used to analyze the prediction of adverse pregnancy outcome of FGR by cerebral placenta rate, umbilical artery flow and middle cerebral artery blood flow. And the sensitivity and specificity of FGR diagnosed were analyzed by calculating area under curve (AUC) and comparing each blood flow index. Results The CPR at 28-31+ 6 weeks of gestation and 32-36+ 6 weeks of gestation were superior to those of umbilical artery and middle cerebral artery blood flow. AUC values at 28-31+ 6 weeks of gestation and 32-36+ 6 weeks of gestation were 0.82 and 0.96, with cutoff values of 1.74 and 1.59. Their sensitivity was 96% and 90%, and the specificity is 79% and 97%, respectively. Conclusion CPR was clinically useful as a predictor of FGR. Key words: Fetal growth retardation; Placental insufficiency; Middle cerebral artery; Ultrasonography, doppler, color