Year-end Sale % OFF 
Abstract
Parkinson disease (PD) was a common insidious neurodegenerative disorder that occurs in middle-aged and elderly people, where the dopaminergic neurons in the midbrain substantia nigra (Dopamine, DA) die over time and the main clinical manifestations are resting tremor, motor bradykinesia, rigidity and eventual inability to control motor functions [1] The specific pathogenesis of PD was complex and not yet clear, but misfolding and aggregation of α-synuclein (α-Syn) is considered to be the hallmark of PD. Since early diagnosis of the disease is difficult, this review summarizes how α-Syn is involved in several aspects into neuronal function and recent advances in targeting α-Syn for PD, providing a theoretical basis for subsequent treatment of PD.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
