Abstract
With the rapid development of the next generation sequencing, it is believed that the lower respiratory tract has been confirmed to have a variety of different microbial communities.At the same time, more and more researches have proved that the microbiome plays an important role in the development of immune system.The disorder of microbiome in respiratory tract may be closely related to various respiratory diseases, including tuberculosis, chronic obstructive pulmonary disease and asthma.This article mainly reviewed the research of respiratory tract microbial of asthma patients and healthy people in recent years, analyzed the change trend of bacterial colonization in the respiratory tract of patients with asthma and the relationship between the changes of respiratory tract microbiome and the pathogenesis of asthma, and discussed the research progress of respiratory tract microbiome in the treatment of asthma. Key words: Microbiome; Asthma; Immunity
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