The research on changes in motilin and gastrin levels of premature infants' blood under developing care

Abstract

Objective To give premature infants developing care and collect the information of the developing care's influence on secretion of motilin and gastrin of premature infants' blood. Methods The newborn patients were divided into the control group and the observation group at random using the random number table. 45 cases in the control group used the premature infants conventional care. 45 cases in the observation group adopted the developing care. We used the radioimmunological analysis (RIA) to determine the changes of motilin (MOT) and gastrin (GAS) of premature infants' blood. Results The values of MOT in the third day were (194.19±54.95)ng/L in the control group and (227.43±85.98)ng/L in the observation group, with P value of 0.032; those in the 10th day were (266.00±71.98) ng/L in the control group and (293.42±2.02) ng/L in the observation group, with P value of 0.041. The differences were significant (P＜0. 05). The values of GAS in the third day were (57.64±18.11)ng/L in the control group and (73.88±35.90)ng/L in the observation group, with P value of 0.009; those in the 10th day were (68.25±23.53)ng/L in the control group and (79.46±24.50)ng/L in the observation group, with P value of 0.029. The differences were significant (P＜0.05). Conclusions The developing care methods can promote the release of gastrointestinal hormone in premature infants' blood, promote the early establishment and further development and mature of digestion functions, and increase the antioxidation function of certain parts of gastrointestinal tract, whereby protecting the intestinal mucosa of new infants to a certain extent. Key words: Premature infants; Developing care; Motilin; Gastrin