The relationship of the environmental effect of surfactants to their interfacial properties

Abstract

AbstractIn an investigation of possible relationships between interfacial properties of surfactants and their environmental effect, using several anionic and nonionic surfactants, a linear correlation was found between the parameters, ΔG0ad/Amin, and rotifer toxicity. ΔG0ad is a standard free energy of adsorption at the air/aqueous solution interface, and Amin is the minimal hydrated cross‐sectional area of the surfactant molecule. Both quantities were evaluated from surface tension data. This correlation is much better than attempted correlations of the toxicity with the negative logarithm of the critical micelle concentration (−log CMC) or with ΔG0ad or Amin alone. The ΔG0ad/Amin correlation with rotifer toxicity is also better than the correlation with the analogous parameter, Δs|Gads0| Amin, obtained from adsorption isotherms of the surfactants on a solid immobilized membrane simulating a cell membrane. The data support our hypothesis that toxicity is determined both by adsorption tendency and ease of cell membrane penetration.