The Relationship Between Occupation Transition Status and Metabolic Syndrome in Adult Women: Tehran Lipid and Glucose Study.

Abstract

Although occupation status may play a role in the risk of metabolic syndrome (MetS), data on this topic are limited. The aim was to examine the association between occupation transition status and the 12-year incidence of MetS in adult women of a population-based cohort study. A total of 2406 women, aged ≥20 years, were selected from the Tehran Lipid and Glucose Study. Subjects were free of MetS at baseline and followed for a mean of 12 years. Based on occupation transition from baseline to the end of follow-up, women were classified into four groups: employed-employed (group I), employed-unemployed (group II), unemployed-employed (group III), and unemployed-unemployed (group IV). The odds ratio (OR) for the occurrence of MetS and its components according to occupation transition status was assessed by multivariate logistic regression. The incidence of MetS in group I and group IV was 15.6% and 29.3%, respectively. In comparison with women in group I, those in group IV had higher risk of MetS (OR = 2.45, 95% CI, 1.6-3.8); however, after adjustment for age, education level, marital status, smoking, and body mass index, the association between occupation status and MetS was not significant (OR = 1.38, 95% CI, 0.83-2.27). In the fully adjusted model, women who were employed at baseline and unemployed at the end of follow-up had greater risk of incident MetS (OR = 2.26, 95% CI, 1.26-4.06) and low high-density lipoprotein cholesterol (OR = 2.34, 95% CI, 1.40-3.85) compared with those who were constantly employed. Occupation transition from employed to unemployed status was found to increase risk of incident MetS.