Abstract
Purpose To confirm the relationship between anterior chamber angle (ACA) and intraocular pressure (IOP) early after V4c implantable collamer lens (ICL) implantation. Methods Patients were assigned to two groups: (1) right eyes (control group) and (2) left eyes (experimental group), with miosis conducted immediately after ICL implantation in the left eyes. IOP, angle opening distance (AOD), trabecular-iris angle (TIA), and pupil diameter (PD) were compared between two groups at postoperative hours 1, 2, and 24. The relationship between ACA, PD, and IOP was analyzed by multiple linear regression. Result Thirty-six eyes of 18 patients were enrolled. The prevalence of ocular hypertension (OHT, defined as IOP ≥ 21 mmHg) was 61.11% and 16.67% in the right and left eyes, respectively, (χ2 = 7.481, p=0.006). At postoperative hours 1 and 2, IOP and PD were significantly higher (p < 0.001) in the right eyes, and TIA and AOD were significantly lower (p < 0.05) in the right eyes than in the left eyes. There was no significant difference at 24 h postoperative in these parameters. After the right eye ICL implantation, the changes of AOD 500 and PD were both linearly correlated with postoperative IOP change (β = −23.707 and 1.731, respectively; p = 0.013 and 0.002, respectively). Conclusion The ACA was significantly narrowed immediately after V4c ICL implantation. There was a negative linear correlation between ACA and early IOP and a positive linear correlation between PD and early IOP. We recommend the use of intracameral miotics immediately after V4c ICL implantation to reduce the incidence of IOP spikes.
Highlights
Introduction e Visian Implantable CollamerLens (ICL) (STAAR Surgical Co., Monrovia, CA, USA) is widely applied to correct refractive errors in patients with moderate to high myopia
Some studies [10, 11] reported that the anterior chamber angle (ACA) narrowed by 39–45% 1 month after surgery of V4c Implantable CollamerLens (ICL) implantation, and the mean intraocular pressure (IOP) was higher than that before surgery. e aim of this study was to access the probable relationship between narrowed ACA and the high rate of ocular hypertension (OHT) within 24 h after V4c ICL implantation and to determine if miosis was effective in control of early IOP
Preoperative and postoperative (1, 2, and 24 hours) data of the right and left eyes are summarized in Table 1. e data of IOP, trabecular-iris angle (TIA) 500, TIA 750, angle opening distance (AOD) 750, and vault in the right or left eyes at each time points were accorded with normal distribution (p > 0.05), and they were presented as mean ± standard deviation (SD)
Summary
Introduction e Visian Implantable CollamerLens (ICL) (STAAR Surgical Co., Monrovia, CA, USA) is widely applied to correct refractive errors in patients with moderate to high myopia. Chen and Sri found that the prevalence of OHT was 31.82% [8] and 60% [9] at 24 h after V4c ICL implantation and that most OHT occurred within 1 h. OHT can lead to irreversible damage to the optic nerve, and the high rate of OHT in the early postoperative period is worthy of attention. Some studies [10, 11] reported that the ACA narrowed by 39–45% 1 month after surgery of V4c ICL implantation, and the mean IOP was higher than that before surgery. E aim of this study was to access the probable relationship between narrowed ACA and the high rate of OHT within 24 h after V4c ICL implantation and to determine if miosis was effective in control of early IOP Some studies [10, 11] reported that the ACA narrowed by 39–45% 1 month after surgery of V4c ICL implantation, and the mean IOP was higher than that before surgery. e aim of this study was to access the probable relationship between narrowed ACA and the high rate of OHT within 24 h after V4c ICL implantation and to determine if miosis was effective in control of early IOP
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