Abstract
This study aimed to investigate the time courses of angle opening parameters and the relationships of these with the corneal endothelial cell density (ECD) and the intraocular pressure (IOP) after posterior chamber phakic intraocular lens (Visian ICLTM, STAAR Surgical) implantation. We evaluated 116 eyes of 59 consecutive patients (mean age ± standard deviation, 34.0 ± 8.8 years) who underwent V5 implantable collamer lens (ICL) implantation. Preoperatively and 1 day, 1 week, and 1, 3, and 18 months postoperatively, we quantitatively measured the angle opening distance at 500 µm (AOD500), the trabecular-iris space area (TISA500), and the trabecular iris angle (TIA500), using anterior segment optical coherence tomography (CASIA 2, Tomey), and assessed the relationships of these measurements with ECD and IOP in ICL-implanted eyes. All angle parameters (AOD500, TISA500, and TIA500) significantly decreased 1 day postoperatively but remained stable thereafter. At 18 months postoperatively, we found no significant correlations of the angle parameters with ECD (Pearson correlation coefficient r = −0.108, p = 0.249 for AOD500; r = −0.162, p = 0.083 for TISA500; r = −0.022, p = 0.815 for TIA500) or between the angle parameters and IOP (r = −0.106, p = 0.256 for AOD500; r = −0.021, p = 0.826 for TISA500; r = −0.018, p = 0.850 for TIA500). The angle opening metrics significantly decreased immediately after ICL implantation but remained stable thereafter. Narrowing of the angle did not significantly affect ECD or IOP in ICL-implanted eyes during the 18-month postoperative period.
Highlights
The EVO Visian Implantable Collamer Lens (ICLTM, STAAR Surgical, Monrovia, CA, USA), a posterior chamber phakic intraocular lens, has become widely accepted as an effective treatment of moderate to high ametropia, over a long period of time [1,2,3,4]
At 18 months postoperatively, we found no significant association between the angle parameters and the endothelial cell density (ECD) (Pearson correlation coefficient r = −0.108, p = 0.249 for AOD500; r = −0.162, p = 0.083 for trabecular-iris space area at 500 μm (TISA500); r = −0.022, p = 0.815 for trabecular iris angle at 500 μm (TIA500)) or between the angle parameters and the intraocular pressure (IOP) (r = −0.106, p = 0.256 for AOD500; r = −0.021, p = 0.826 for TISA500; r = −0.018, p = 0.850 for TIA500)
Our findings showed that all angle opening parameters (AOD500, TISA500, and TIA500) significantly decreased immediately after implantable collamer lens (ICL) surgery, but the parameters remained unchanged thereafter
Summary
The EVO Visian Implantable Collamer Lens (ICLTM, STAAR Surgical, Monrovia, CA, USA), a posterior chamber phakic intraocular lens, has become widely accepted as an effective treatment of moderate to high ametropia, over a long period of time [1,2,3,4]. The detailed time course of angle opening metrics has not been fully elucidated in ICL-implanted eyes, especially in the early postoperative period. To the best of our knowledge, the effects of these angle metrics on ECD and IOP levels have so far not been investigated in such eyes. This may give us intrinsic insights on the clinical implication of the angle opening after ICL implantation. The goal of the present study was twofold: (1) to assess the time course of changes in the angle opening parameters and (2) to investigate the relationships of (1) with the ECD and the IOP in eyes undergoing ICL implantation
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