Year-end Sale % OFF 
Abstract
Summary. Neutrophils, apart from their role in immunodefence, are also connected with lung injury, because of excessive release of enzymes such as elastase and myeloperoxidase (MPO), as well as nitric oxide (NO) generation. The purpose of this study was the relation between release of neutrophil products, acute phase proteins level (APP) and ascorbic acid (AA) concentration in the course of BRD in calves. The study was carried out on 10 healthy and 10 BRD calves. Neutrophil enzymes were assessed spectrophotometrically, NO level was determined by Griess reaction. Fibrinogen level was estimated by the heat precipitation method. Haptoglobin was assessed by the Owen’s method. AA analysis was done after reaction with dinitrophenyhydrazine. We estimated that elastase (71.97 ± 3.89%) and MPO (29.7 ± 5.88%) release from neutrophils isolated from BRD calves was significantly higher than from healthy animals (54.23 ± 5.66% and 19.18 ± 8.3%, respectively, p < 0.05). Moreover, our experiment revealed the positive correlation between secretory action of neutrophils and APP. We also observed that increased secretory action correlated negatively with plasma concentration of AA.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
