The Rate of Elevated Antenatal Edinburgh Depression Score in Pregnancies Complicated by Gestational Diabetes [12Q

Abstract

INTRODUCTION: The US Preventative Task Force recommends depression screening in pregnancy. The Edinburgh Depression Scale (EDS) is a self-administered screening tool for the diagnosis of depression. An EDS of greater than or equal to 10 is considered elevated and correlated with depression. Despite correlation with depression, maternal and neonatal outcome in high risk populations is unclear. METHODS: This is a retrospective study of singleton pregnancies with gestational diabetes at UC San Diego between 2010-2014 with an antepartum EDS. The primary outcome was the rate of elevated EDS and referral for treatment. The secondary outcomes included maternal characteristics, perinatal outcome, and postpartum follow-up. RESULTS: 210 women met inclusion criteria. 53.2% (107/210) had an elevated EDS score and 71% (76/107) were referred for counseling. Of these, 24.5% (26/76) attended their counseling appointments. 18.7% (20/107) received pharmacologic treatment. Patients with a positive EDS score had a higher rate of PTD (19.6% vs 9.7% (p=0.05)), higher rate of obesity, and less weight gain. No statistical differences were noted in SGA, however, a trend toward a higher rate of these outcomes were noted in the group with elevated EDS (SGA 9.4% vs 2.9% (p=0.08). There were no differences in delivery method, rates of macrosomia, and diabetic control. CONCLUSION: 53% of women with gestational diabetes had an elevated antenatal EDS and approximately 44.9% received treatment. Despite these interventions, a higher rate of PTD and lower weight gain was noted in those with an elevated EDS. Further studies are needed to determine the best intervention and its effect on perinatal outcomes.