Abstract
Aim: Allium cepa is consumed fresh or cooked in Nigeria and used as herb in ethnomedicinal practice against many ailments. The aqueous extract is used in the management of prostrate inflammation, alleviation of low sperm count and testicular damage related disorders in ethno medicine and folkloric medicine in the South-east regions of Nigeria. This study investigates the protective role of extract of Allium cepa bulb on spermatogenesis and testicular oxidative stress in male rats using Artesunate as testicular damage and oxidative stress inducing agent. Study Design and Methodology: The design consisted of 5 groups of 10 male Wistar rats (140-180g) each. Groups 1, 2, 3 and 5 were given continuous oral challenge with 4.4mg/kgb.w Artesunate orally for two weeks to induce testicular damage. Animals were treated with 50, 150 and 300mg/kgb.w extract for 7 weeks. Groups 4 and 5 were not
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