Abstract
Collagen hydrogel is an attractive material for biomedical applications as it is the most abundant protein in mammalian tissues and is the main component of natural extracellular matrices. The study aims to identify the hydrogel's performance prepared by UV and heat cure and investigate the effect of graphene oxide (GO) on the properties of heat cure hydrogel. The hydrogels were prepared with two different curing methods using Irgacure2959 and potassium persulfate as crosslinkers in this work. GO acts as filler was added in the hydrogel to form a composite hydrogel. The hydrogels were characterized using compression test, swelling test, and thermogravimetric analysis (TGA). This study found that the heat-cured hydrogel exhibited higher compression properties than that prepared by the UV curing method. The results follow the swelling test. Adding GO in the heat-cured hydrogel improved the compression strength of composite hydrogel by 56% compared to the unfilled hydrogel. The thermal stability of hydrogel showed two decomposition steps, one in the range of 100–200 °C related to the loss of water and another in the range of 300–400 °C associated with degradation of the collagen structure. Results showed that the GO composite has higher thermal stability than an unfilled hydrogel.
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