Abstract
The increasing demands for implants due to aging and orthopedic necessitate advancements in coating technologies to enhance implant performance, especially when it comes to the infections and inflammation at the implantation site. The development of bioactive coatings with antibacterial properties, superior adhesion, and the controlled release of antibacterial agents is of significant importance. This study investigates the application of pectin/ɛ-polylysine (ɛ-PL) composite coatings on anodized titanium surfaces, with the aim of improving the bioactivity, biocompatibility, and antibacterial properties of the anodized surface. The multifunctional nature of these coatings addresses critical challenges associated with successful implantatins and offers promising solutions for biomedical applications. The anodization was first carried out at 40 V, followed by the dip coating of the pectin/ɛ-PL layer. Fourier-transform infrared (FTIR) analysis, field emission scanning electron microscope (FE-SEM), energy-dispersive X-ray spectroscopy (EDS) analysis, and laser profilometry were used to investigate the surface structure and the roughness of the applied layer. Corrosion tests, and MTT/anti-bacterial assays were utilized to investigate the electrochemical and biomedical properties of applied coating layers. Results indicated that pectin-1 % ɛ-PL exhibited excellent anti-bacterial properties, with cell viability above 50 %. Apatite crystals were also formed on coated specimens after 2-weeks of immersion in simulated body fluid (SBF), implying that applied coating layers are bioactive. Adhesion tests showed a remarkable improvement in mechanical properties of pectin top layer with the addition of ɛ-PL. Overall, the pectin-ɛ-PL composite coating exhibited some interesting properties, making it a promising easy-to-apply top coat on anodized surfaces in biomedical applications.
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