Abstract
Background Post-operative cognitive dysfunction (POCD) happens at a higher incidence rate in elderly patients. Microglia is a kind of glial cell in central nervous system (CNS), which plays an important role in both the physiological and the pathological processes in CNS. A growing number of studies have demonstrated that microglia is involved in the development of multiple neurodegenerative diseases. Objective To review and discuss the role of microglia in the formation of POCD. Content In this review, we make a summary on the regulatory effects of microglia on learning and memory as well as on correlations between microglia and POCD. Trend The function of microglia in POCD is still not elucidated. Further in-depth research in this field may provide new ideas for the prevention and the treatment of POCD. Key words: Microglia; Learning; Memory; Cognitive function; Surgery
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Anesthesiology and Resuscitation
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
