Abstract

Aim: Percutaneous mitral valve repair (PMVR) with MitraClip® has proven to be an effective therapy to reduce mitral regurgitation in patients at high risk for conventional surgery. This population is currently characterized by advance age and high prevalence of comorbidities. Our aim was to evaluate the prevalence of frailty in a cohort of patients undergoing PMVR and its impact on clinical outcomes during follow-up.

Highlights

  • In the last decade, percutaneous mitral valve repair (PMVR) with MitraClip® device (Abbot Vascular, Santa Clara, USA) has proven to be an effective therapy to reduce mitral regurgitation (MR), with a low incidence of complications in patients deemed as high-risk candidates or unfit for conventional surgery[1]

  • Frailty was common in patients undergoing PMVR in our institution

  • Despite post-procedural clinical improvement, frailty was related to adverse outcomes in our series

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Summary

Introduction

Percutaneous mitral valve repair (PMVR) with MitraClip® device (Abbot Vascular, Santa Clara, USA) has proven to be an effective therapy to reduce mitral regurgitation (MR), with a low incidence of complications in patients deemed as high-risk candidates or unfit for conventional surgery[1]. Risk stratification in these patients is challenging and it is usually based on non-dedicated risk scores developed in the surgery field, with a modest predictive value in this scenario[2]. The main objective of our study was to assess the prevalence of frailty in a cohort of patients undergoing PMVR, and to assess its impact on clinical outcomes during follow-up

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