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Article1 October 1947THE PROGNOSIS OF SYPHILITIC AORTIC INSUFFICIENCYGEORGE G. READER, BRUNO J. ROMEO, BRUCE WEBSTER, WALSH MCDERMOTTGEORGE G. READERSearch for more papers by this author, BRUNO J. ROMEOSearch for more papers by this author, BRUCE WEBSTERSearch for more papers by this author, WALSH MCDERMOTTSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-27-4-584 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe course of syphilitic aortic insufficiency is generally believed to be rapidly progressive.1, 2, 3, 4, 5, 6 Death from cardiac failure is said to occur 12 to 36 months after the discovery of the lesion,7 although Grant8 in a study of 1,000 cardiac patients showed that the 10-year case fatality rate of syphilis of the aortic valve is only 64 per cent. It has been reported that antisyphilitic therapy doubles the life expectancy in this disease.3In a previous study from this clinic9of a large group of patients with aortic valvular syphilis, it was observed that current prognostic...Bibliography1. WHITE PD: Heart disease, 1944, The Macmillan Company, New York, p. 384. Google Scholar2. LEVINE SA: Clinical heart disease, 1946, W. B. Saunders Company, Philadelphia, p. 155. Google Scholar3. MOORE JE: The modern treatment of syphilis, 1944, Charles C. Thomas Company, Baltimore, p. 284. Google Scholar4. YATER WM: Fundamentals of internal medicine, 1940, Appleton-Century, New York, p. 28. Google Scholar5. LAMBTURNER ARKB: Nelson's loose-leaf medicine, 1932, Thomas Nelson and Sons, New York, p. 394A. Google Scholar6. TICE F: Tice's Practice of medicine, 1944, Prior Company, Hagerstown, Maryland, p. 300. Google Scholar7. WHITE PD: Cecil's Textbook of medicine, 1943, W. B. Saunders Company, Philadelphia, p. 1092. Google Scholar8. GRANT RT: After histories for ten years of a thousand men suffering from heart disease. A study in prognosis, Heart, 1931-33, xvi, 276. Google Scholar9. MCDERMOTTTOMPSETTWEBSTER WRB: Syphilitic aortic insufficiency: The asymptomatic phase, Am. Jr. Med. Sci., 1942, cciii, 202. CrossrefGoogle Scholar10. FARROPPENHEIMERSAGER LBSRV: The circulation time in various clinical conditions using sodium dehydrocholate, Am. Heart Jr., 1933, viii, 766. Google Scholar11. GOLDBERG SJ: The use of calcium gluconate as a circulation time test, Am. Jr. Med. Sci., 1936, cxcii, 36. CrossrefGoogle Scholar12. UNGELEIDERCLARK HECP: A study of the transverse diameter of the heart silhouette with prediction table based on the teleroentgenogram, Am. Heart Jr., 1939, xvii, 92. CrossrefGoogle Scholar13. KAMPMEIER R: Essentials of syphilology, 1944, J. B. Lippincott Company, Philadelphia, p. 319. Google Scholar14. PADGETMOORE PJE: The results of treatment in cardiovascular syphilis, Am. Heart Jr., 1935, x, 1017. CrossrefGoogle Scholar15. CHRISTIAN HA: Osler's Principles and practice of medicine, 1944, Appleton-Century, New York, p. 414. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication February 21, 1947.From the Department of Medicine, Cornell University Medical College and The New York Hospital.The work described in this paper was done under a grant-in-aid from the U. S. Public Health Service and the Barbara Whitney Henry Research Fund. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcquired Lesions of the Aortic ValveErworbene Vitien der AortenklappeNatural History of Aortic RegurgitationCase 31-1967Die koronare Blutversorgung bei den Klappeninsuffizienzen des linken HerzensSYPHILITIC AORTIC INCOMPETENCEObservations on Penicillin Therapy in Cardiovascular SyphilisA clinical study of one hundred cases of severe aortic insufficiencyCardiovascular Syphilis: A CLINICAL STUDY OF 578 CASESPenicillin Treatment of Cardiovascular SyphilisTreatment of Cardiovascular SyphilisSYPHILITIC HEART DISEASE IN THE AGED*FREDERIC D. ZEMAN, M.D., F.A.C.P., SIDNEY STORCH, M.D.Penicillin Treatment of Patients with Cardiovascular Syphilis in Congestive FailurePenicillin therapy of cardiovascular syphilisSyphilis 1 October 1947Volume 27, Issue 4Page: 584-595KeywordsAortic valveHeart failureHeart rateHospital medicineLife expectancyMedical servicesResearch fundingSyphilis ePublished: 1 December 2008 Issue Published: 1 October 1947 PDF downloadLoading ...

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