Abstract

1. 1. Microorganisms, isolated from human saliva, carious dentine, and periodontal pockets, which produced both beta-glucuronidase and hyaluronidase were alpha hemolytic streptococci, Streptococcus mitis. 2. 2. The finding of three different strains of Streptococcus mitis is reported. 3. 3. Beta-glucuronidase and hyaluronidase titers from Streptococcus mitis were found to parallel one another. 4. 4. Beta-glucuronidase produced by Streptococcus mitis was found to be predominantly extracellular. 5. 5. Optimum conditions for the assay of beta-glucuronidase activity by Streptococcus mitis are described. 6. 6. The effect of sucrose in acid production on hyaluronidase and beta-glucuronidase activity by Streptococcus mitis was measured.

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