Abstract
Painful diabetic neuropathy is a frequent complication of diabetes. Its diagnosis is clinical. Our goal is to determine the prevalence of painful diabetic neuropathy in this population. We also analyzed the relationship between this neuropathy and certain parameters, concerning the patient and his diabetes. It is a cross sectional study conducted at the department of endocrinology and internal medicine of Avicenne hospital Marrakech-Morocco, among a cohort of 300 diabetic outpatients. We used the DN4 questionnaire (Douleur Neuropathique en 4 questions), for diagnosis. The results showed a prevalence of 15%. In this study: advanced age, female gender, duration of diabetes greater than 10 years, and the lack of medical follow up were found to be statistically significant risk factors for painful diabetic neuropathy, in addition to some diabetes-related comorbidities such as hypertension, dyslipidemia, sedentary life style and diabetic retinopathy. Painful diabetic neuropathy remains undertreated, in fact 74% of our patients did not receive any specific treatment, knowing that the progress in developing effective and well-tolerated therapies has been disappointing.
Highlights
Diabetes mellitus is one of the biggest global health problems of the 21st century
Diabetes could lead to serious complications; in this study we were interested in the painful form of peripheral neuropathy
We have determined the prevalence of painful diabetic neuropathy (PDN) and its potential risk factors
Summary
Diabetes mellitus is one of the biggest global health problems of the 21st century. Its global prevalence in adults aged 20-79 years was estimated to be 8.8% [1]. Diabetes could lead to serious complications; in this study we were interested in the painful form of peripheral neuropathy. The prevalence of painful diabetic neuropathy (PDN) varies between 10% and 60% [2]. PDN can have debilitating consequences with significant impact on the quality of life and cost of care. The diagnosis is clinical, based on clinical finding, and has been facilitated by the development of simple and validated questionnaires, such as the neuropathic pain 4 questions (DN4) [4]. We have determined the prevalence of PDN and its potential risk factors
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