Abstract

BackgroundDyslipidemia is an important independent modifiable risk factor for cardiovascular disease. The aim of this study was to explore the current prevalence, awareness, treatment and control of dyslipidemia and its associated influence factors in northeast China.MethodsIn this population-based cross-sectional study, we adopted a multi-stage, stratified sampling method to obtain a representative sample of 4052 permanent residents aged 40 years and over from different urban and rural regions in Dehui City of Jilin Province. All subjects completed a questionnaire and were examined for risk factors. Continuous data were presented as means ± standard deviations (SD) and compared using the Student’s t-test. Categorical variables were presented as proportions and compared using the Rao-Scott-χ2 test in different subgroups. The associated influence factors for the prevalence, awareness, treatment and control of dyslipidemia were evaluated through multivariate logistic regression.ResultsThe prevalence of dyslipidemia was 62.1% overall, with 33.5, 43.9, 0.6, and 8.8% for high total cholesterol, triglyceride, low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol, respectively. Among those with dyslipidemia, the proportion of subjects who were aware, treated, and controlled was 14.4, 33.9, and 19.9%, respectively. Overweight or obesity (OR = 2.156; 95% CI: 1.863, 2.533), hypertension (OR = 1.643; 95% CI: 1.425, 1.893), or diabetes mellitus (OR = 2.173; 95% CI: 1.661, 2.844) increased the prevalence of dyslipidemia, also these participants were more likely to be aware of their condition, however, this did not increase the likelihood of treatment and control. Living in urban areas and higher education level also increased the awareness of dyslipidemia. Personal history of coronary heart disease was the strongest influence factors associated with better awareness, treatment and control of dyslipidemia. Overweight or obesity (OR = 0.404; 95% CI: 0.235, 0.695) and lack of exercise (OR = 0.423; 95% CI: 0.215, 0.830) were associated with poor control of dyslipidemia.ConclusionThe prevalence of dyslipidemia among adults aged 40 years and over in northeast China was high, however, the awareness, treatment, and control of dyslipidemia was measured at far from desirable levels. Renewed efforts taking influence factors into account are needed to improve the current unsatisfactory condition.

Highlights

  • Dyslipidemia is an important independent modifiable risk factor for cardiovascular disease

  • Compared with the non-dyslipidemia group, we found that the dyslipidemia group had a higher prevalence of hypertension, diabetes mellitus, overweight or obesity, lack of exercise, personal and family history of stroke and coronary heart disease, family history of dyslipidemia, and central obesity (p < 0.001, except p < 0.05 for family history of stroke)

  • The prevalence of dyslipidemia showed no statistically significant difference between males and females (61.3% vs. 62.9%, p = 0.383), but that of low high-density lipoprotein cholesterol was significantly higher in males than females (11.1% vs. 6.4%, p < 0.001), yet the opposite was true for high total cholesterol (31.6% vs. 35.5%, p = 0.031)

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Summary

Introduction

Dyslipidemia is an important independent modifiable risk factor for cardiovascular disease. The latest data from Jilin Province in northeast China reported that the awareness, treatment, and control rate of dyslipidemia were 11.6, 8.4, and 34.8%, respectively, in 2012 [14]. The 2015–16 Stroke Screening and Prevention Program of the National Health and Family Planning Commission of China Study includes these data and remains the latest cross-sectional survey in northeast China. Based on this survey database, we analyzed the current prevalence, awareness, treatment, and control of dyslipidemia and its associated influence factors in Jilin Province, northeast China

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