Abstract

Aldolase A and hybrid molecules between aldolases A and C in a strain of Yoshida ascites hepatoma, AH143A of rat were found by electrophoresis on a cellulose acetate membrane. Results of column chromatography and inhibition by anti-aldolase A confirmed the presence of A 3C hybrid molecule in this hepatoma. The significance of the aldolase C peptide in the hepatoma is discussed in relation to dis-differentiation.

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