Abstract

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a condition related to cancer treatment. Although various drugs and protocols are recommended for prophylactics and treatment, no strategies have yet been proven effective completely. Several drug treatment regimens have been proven for neuropathy, which includes calcium channel blockers, opioids, anti-depressants, and anticonvulsants, but they are only partially effective and have adverse effects associated with their administrations that diminish the quality of life and an economic burden is imposed on the patient. On the one hand, to treat peripheral neuropathy, a single therapeutic agent is not sufficient. On the other hand, Plants are the source of a vast number of bioactive phytochemicals which can potentially treat disease and related complications together

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