Abstract
Phenolic compounds constitute a group of secondary metabolites which have important functions in plants. Besides the beneficial effects on the plant host, phenolic metabolites (polyphenols) exhibit a series of biological properties that influence the human in a health-promoting manner. Evidence suggests that people can benefit from plant phenolics obtained either by the diet or through skin application, because they can alleviate symptoms and inhibit the development of various skin disorders. Due to their natural origin and low toxicity, phenolic compounds are a promising tool in eliminating the causes and effects of skin aging, skin diseases, and skin damage, including wounds and burns. Polyphenols also act protectively and help prevent or attenuate the progression of certain skin disorders, both embarrassing minor problems (e.g., wrinkles, acne) or serious, potentially life-threatening diseases such as cancer. This paper reviews the latest reports on the potential therapy of skin disorders through treatment with phenolic compounds, considering mostly a single specific compound or a combination of compounds in a plant extract.
Highlights
The skin has many functions in humans, especially in the defense against physical, chemical or biological factors
The purpose of this review is to present data on health-promoting properties of plant phenolics, both isolated pure components and mixtures naturally occurring in plant extracts, in the context of prevention and treatment of skin disorders, such as the premature effects of aging, skin diseases, as well as severe skin damage in the form of injuries
It has been known for a long time that phenolic compounds occurring naturally in plants present a broad spectrum of health-promoting properties resulting from their biological activity
Summary
The skin has many functions in humans, especially in the defense against physical, chemical or biological factors. Phenolic compounds are found to be one of the most important groups of plant secondary metabolites, due to their great participation in morphological development, physiological processes and reproduction. These phytochemicals are synthesized through the pentose phosphate, shikimate and phenyInlt.pJ.rMoopl. Resveratrol (trans-3,5,4’-trihydroxystilbene) is present in many plant species, including those that are popular components of the human diet such as grapes, peanuts, and berries. Plants synthetize it as a part of defense mechanisms against mechanical injury, pathogen infection, and UV radiation. Sunflower seeds, sezame seeds, grains, carrot, onion, chives, apples, cherries, blueberries, strawberries, nuts, tea, coffee
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