Abstract
Soft coral is one of the marine organisms that produce secondary metabolites materials and has potency as anticancer. There is much research to find bioactive compounds in the organism, but it still lacks data to find potency of bioactive in soft coral that lives under acidification pressure. The objectives of this study are to determine the characteristic of acidification in Krakatau seas and to assess the potency of cytotoxic activity from soft coral Sarcophyton. Sampling was conducted in three locations, Legon Tuo, Legon Cabe, and Umang-umang Island, to take the sample and measure water quality. Cytotoxic test using MTT method (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolinon) to MCF-7 cancer cell line to measure growth inhibition percentage. Data were analyzed using ANOVA, post hoc analysis, and multivariate analysis. Water quality in Legon Tuo and Legon Cabe have significant different to Umang-umang Island. However, Legon Tuo and Legon Cabe are suitable as acidification site, while Umang-umang Island as the reference site. The characteristic of Krakatau seas, especially in Legon Tuo and Legon Cabe study site, was categorized in low acidification. In the cytotoxic activity, soft coral Sarcophyton from Legon Cabe (acidification site) is more potential than soft coral from Umang-umang Island (reference site).
Highlights
Krakatau islands are formed from a big eruption activity and have built new four small islands at the same place, named RakataIsland, Sertung Island, Panjang Island, andAnak Krakatau Volcano that have continued eruption activity
Putra et al, (2014) stated that the succession process which was happened around Anak Krakatau volcano was categorized as the beginning state of the settlement, while in Rakata and Sertung Island have indicated with diversification in the coral community from opportunist and pioneer species (Pocillopora and Seriatopora)
This area with volcanic activity certainly produces natural carbon dioxide that can lead to decreasing in pH
Summary
Krakatau islands are formed from a big eruption activity and have built new four small islands at the same place, named RakataIsland, Sertung Island, Panjang Island, andAnak Krakatau Volcano that have continued eruption activity. Putra et al, (2014) stated that the succession process which was happened around Anak Krakatau volcano was categorized as the beginning state of the settlement, while in Rakata and Sertung Island have indicated with diversification in the coral community from opportunist and pioneer species (Pocillopora and Seriatopora). This area with volcanic activity certainly produces natural carbon dioxide that can lead to decreasing in pH (acidification). This condition can be a reference to the biological changing marine organism that lives in lower pH habitat (UNEP, 2010). With decreasing in pH, it triggered in declining of calcification process, polyp growth, and zooxanthellae cell density on Scleractinian corals (Januar et al, 2016a)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
