Abstract

The ribonucleic acid level in the lungs and liver of albino mice and guinea pigs proved to increase considerably under the effect of immunization with the BCG vaccine. Infection with a virulent tuberculosis strain provoked a considerable rise of the ribonucleic acid concentration in the lungs of albino mice relatively resistant to tuberculosis, whereas the organs of guinea pigs sensitive to tuberculosis exhibited a normal range of variations in the ribonucleic acid level. It is suggested that the rise of the ribonucleic acid level in the organs of the immunized animals and in the lungs of the infected mice is connected with the mechanism of artificial immunity and natural resistance to tuberculosis.

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