The pilot study of the central venous pressure of very low birth weight infant within 1 week after birth

Abstract

Objective To study the range of central venous pressure (CVP) in very low birth weight (VLBW) infants within the first week after birth. Method From February 2014 to February 2018, 50 VLBW infants without serious diseases during the first 7 days of life received umbilical venous catheters were prospectively enrolled. CVPs were measured every 4~6 h. The trend of CVP and the correlation of CVP (within 24 h) and birth weight, gestational age were analyzed. Result A total of 50 VLBW infants and 1 291 CVP measurements were included. The CVP increased slightly within 48 h after birth, and then declined. The 95%CI of CVPs were 3.67~4.21, 4.03~4.49, 3.90~4.33, 3.67~4.19, 3.29~3.97, 3.14~3.94 and 2.64~3.55 cmH2O from day 1 to day 7. No significant correlation existed between CVP in the first day and birth weight,nor gestational age (r=-0.267, P=0.073; r=0.106, P=0.762). Conclusion The CVP of VLBW infants increased slightly within 48 h after birth, and then declined. There was no significant correlation between CVP in the first day and birth weight, nor CVP and gestational age. Key words: Central venous pressure; Infant, very low birth weight; Infant, premature; Umbilical venous catheters