Abstract
Skin renewal is characterised by progenitor cells at the epidermal basal layer dividing and differentiating, yet the identity and properties of these progenitors remain poorly understood. In a new study, Tudorita Tumbar and colleagues identify, for the first time in vivo in the mouse epidermis, a distinct population of non-self-renewing progenitor cells that exhibit biphasic transit-amplifying behaviour. To find out more about the story behind the paper, we caught up with first author Sangeeta Ghuwalewala, penultimate author David Shalloway and corresponding author Tudorita (Doina) Tumbar, Professor of Molecular Biology and Genetics at Cornell University, USA.
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