Abstract
Akt is believed to be important for vascular development, but complex tissue-specific loss-of-function studies have been difficult in mice because of embryonic lethality. In a new study, Wenping Zhou, Joey Ghersi, Stefania Nicoli and colleagues report the phenotype of a complete Akt mutant zebrafish and its role in arterial specification via Notch signaling. To learn more about their work, we spoke with corresponding authors Joey Ghersi, Assistant Professor at Centre Hospitalier Universitaire (CHU) Sainte-Justine, Canada, and Stefania Nicoli, Associate Professor Tenure at Yale University, USA.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
