The para-chloroaniline prevention after the use of sodium thiosulfate as an intermediary irrigator between sodium hypochlorite and chlorhexidine

Marília Alves

doi:10.31579/2640-1045/051

Abstract

Objective: Evaluating the neutralization of sodium hypochlorite (NaOCl) by sodium thiosulfate in vitro, in different concentrations, in the prevention of para-chloroaniline (PCA) formation when in contact with CHX. Material and methods: It were collected 2 mL of NaOCl solution to 2.5% and to 6%, divided in eight groups according to the sodium thiosulfate concentration (1.0; 2.5; 5.0; 10%) (TSF). The tests were done in duplicate and in each plate, it was poured 2mL of TFS and the reaction was observed for 5 minutes. After, 2 mL of 2% Chlorhexidine (CHX) were pouring on the plates to verify the formation of PCA. The infrared spectroscopy with Fourier transform was used to verify the presence of PCA, and, in each solution, the pH was verified with universal strip. Results: All analyzed samples presented presence of water and deuterium water, and there was not identification of the PCA presence. The pH result of the solutions was between 8 and 9. It was verified that in the increasing of the concentration of the TFS there was gradual formation of precipitated compound and increase of the turbidity of the final sample. Conclusion: TFS can be used as an intermediate irrigation solution to prevent the formation of para-chloroaniline in the combined use of NaOCl and CHX.

Highlights

Auctores Publishing – Volume 4(1)-051 www.auctoresonline.org ISSN: 2640-1045J Endocrinology and DisordersCopy rights@ Toledo et al.The disinfection of the root canal system (RCS) is a fundamental factor in the endodontic therapy for the reduction of the number of microorganisms that is in the necro pulpectomy techniques and collaborating to the maintenance of the healthy peri-root tissues or favor this region recuperation when that is a lesion (Siqueira et al 2017)
Copy rights@ Toledo et al The disinfection of the root canal system (RCS) is a fundamental factor in the endodontic therapy for the reduction of the number of microorganisms that is in the necro pulpectomy techniques and collaborating to the maintenance of the healthy peri-root tissues or favor this region recuperation when that is a lesion (Siqueira et al 2017)
The physical action of the irrigator liquid promotes the hydraulic circulation into the root canal, dragging tissues, microorganisms, and dentin scrapings [2]

Summary

Introduction

Auctores Publishing – Volume 4(1)-051 www.auctoresonline.org ISSN: 2640-1045J Endocrinology and DisordersCopy rights@ Toledo et al.The disinfection of the root canal system (RCS) is a fundamental factor in the endodontic therapy for the reduction of the number of microorganisms that is in the necro pulpectomy techniques and collaborating to the maintenance of the healthy peri-root tissues or favor this region recuperation when that is a lesion (Siqueira et al 2017). The endodontic infections are caused by bacterial intra-root biofilms colonizing mainly the light of the main canal. The chemical-mechanical prepare is capable to eliminate a large quantity of micro-organisms, a complete disinfection is hard due to the complex anatomy of the RCS [1.2]. The using of an auxiliary chemical substance during the chemical mechanical prepare is especially important and aims to reach inaccessible areas to the instruments, to promote the additional elimination of microorganisms of the endodontic complex. The physical action of the irrigator liquid promotes the hydraulic circulation into the root canal, dragging tissues, microorganisms, and dentin scrapings [2]. The chemical action of the irrigator substance should have the property of causing the bacteria and fungi death [4]

Methods

Results

Discussion

Conclusion