Abstract

To evaluate an experimental animal model to study the abdominal tissue activity considering its interaction with a polypropylene mesh, through the use of one of the optical phenomena of light Laser, the biospeckle. Fifty Wistar male rats were divided into four groups: Group 1: ten animals not submitted to surgery; Group 2: ten animals submitted to surgery without polypropylene mesh; Group 3: 20 animals submitted to surgery followed by the mesh placement; Group 4: (sham) with ten animals. None of the animals presented post surgical complications being submitted to the optical tests at the 20th postoperative day. The analysis from the biospeckle tests, comparing the medians and standard deviations with T Student test, indicated that no significative difference was observed on the abdominal wall tissue activity in the four groups considered, with and without polypropylene mesh prosthesis implantation. The animal model is viable and the biospeckle open ways for a great number of experiments to be developed in evaluating tissue activity.

Highlights

  • The polypropylene meshs have been used from the end of the fifties, so much in abdominal hernias, as in reconstructions of defects of the abdominal wall after wide tumour exeresis[1,2,3]

  • The optical analysis of the abdominal wall using the biospeckle after implants of polypropylene mesh in rats

  • The present study consisted of the creation of an animal model, that it was shown viable, for the study of the tissue activity of the abdominal wall during the wound healing, so much without prosthesis, as their interactions with prosthesis, through the use of one of the optical phenomena of the Laser (Ligth Amplification by Stimulated Emission of Radiation), the biospeckle

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Summary

Introduction

The polypropylene meshs have been used from the end of the fifties, so much in abdominal hernias, as in reconstructions of defects of the abdominal wall after wide tumour exeresis[1,2,3]. The present study consisted of the creation of an animal model, that it was shown viable, for the study of the tissue activity of the abdominal wall during the wound healing, so much without prosthesis, as their interactions with prosthesis, through the use of one of the optical phenomena of the Laser (Ligth Amplification by Stimulated Emission of Radiation), the biospeckle. That phenomenon has been studied with the intention of developing a fast method and no destructive for evaluation of biological materials[23,24]. It can be evaluated, besides, viability of seeds with the dynamic biospeckle[25]

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