Abstract

Odontogenic keratocyst (OKC) is a unique developmental odontogenic cyst which seem to be controversy’s favourite child since the time of its inception. This lesion has garnered special attention over the last two decades owing to the increasing confusion over its nomenclature and classification. Whether the change in category of OKC ends here or continues in the future will be an interesting watch. This commentary thus provides an insight into the ongoing debate and attempts to provide a constructive criticism on the same.

Highlights

  • Odontogenic keratocyst (OKC) is one of the controversial benign odontogenic pathologies in the maxillofacial region, which has undergone repeated conceptual and terminological changes since the time of inception in 1876 [1]

  • Classified as the developmental odontogenic cyst of the jaw by the World Health Organisation (WHO) in 1971 and 1992, OKC has been reclassified as a benign odontogenic neoplasm by the name of Keratocystic Odontogenic Tumor (KOT) in the third revision of WHO in 2005

  • The OKC has always been a subject of interest to researchers and a conundrum to surgeons and pathologists due to its unique biological behavior, namely its aggressive and infiltrative nature, increased recurrence rate, and the association of multiple OKCs with Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

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Summary

Introduction

Odontogenic keratocyst (OKC) is one of the controversial benign odontogenic pathologies in the maxillofacial region, which has undergone repeated conceptual and terminological changes since the time of inception in 1876 [1]. 1. Department of Oral Pathology and Microbiology, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research, Chennai, India Academy of Higher Education and Research, Chennai, India

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